5 edition of Germ Cell Tumours II found in the catalog.
December 1, 1985
Written in English
|Contributions||C. K. Anderson (Editor)|
|The Physical Object|
|Number of Pages||480|
Germ cell tumours The book begins with a simple definitions page. This is followed by a flow chart titled “How to advise the climacteric woman: the chain of reasoning.” On the opposite page the relevant issues are detailed, to-gether with page numbers indicating where these is-sues are dealt with in the book. The risk of thrombo-embolic events is increased in patients with germ-cell tumours and can be predicted by serum lactate dehydrogenase and body surface area. Br J Cited by:
Germ cell tumors (GCTs) are the most common solid tumors in men between the ages of 15 and 35 years, with an estimated 8, new cases expected in the United States in 1 Initial cisplatin (CIS) combination chemotherapy will cure 70% of patients with disseminated testicular cancer, making it one of the most chemotherapy-sensitive solid tumors, and a model for a curable neoplasm. Cited by: Female malignant ovarian germ cell tumours (MOGCTs) are rare, but early diagnosis and multiagent chemotherapy are 1associated with high cure rates of % (range –%). While sharing many similarities with male germ cell tumours (GCTs), a group of File Size: KB.
Germ cell cancer is a rare tumor that affects children, teens, and adults. About children and adolescents are diagnosed with germ cell tumors in the U.S. each year, comprising about 4% of all childhood cancers. Germ cell tumors most commonly appear in . Through time, these cells can grow into germ cell tumors, also called gonadal germ cell tumors. Germ cell tumors may be cancerous (malignant) or noncancerous (benign). Although germ cells are usually in the reproductive organs, these cells can sometimes travel to other parts of the body and cause tumors, called extragonadal germ cell tumors.
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Between April and March45 patients with relapsing or refractory germ-cell tumours were treated in two successive phase II trials with high-dose chemotherapy and bone marrow rescue as part of salvage treatment.
Thirty-two patients received the PEC protocol (cisplatin + etoposide +cyclophosphamide). Germ cell tumours develop in germ cells. These are the cells in the body that develop into sperm and eggs. Germ cell tumours most often develop in the ovary or testicle because this is where most germ cells are.
But germ cells can sometimes be left behind in other parts of the body from when you developed in the womb. Sometimes, a group of germ cells grows in a way that’s not normal. A tumor forms.
This usually happens in an ovary or testicle. You can also get a germ cell tumor in the brain, chest, belly. A germ-cell tumor (GCT) is a neoplasm derived from germ cells. Germ-cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads (ovary and testis).
GCTs that originate outside the gonads may be birth defects resulting from errors during development of the embryo. 2 Classification.
Germinomatous. lty: Oncology. Ovarian germ cell tumors (OGCTs) are heterogeneous tumors that are derived from the primitive germ cells of the embryonic gonad, which accounts for about % of all ovarian malignancies. There are four main types of OGCTs, namely dysgerminomas, yolk sac tumor, teratoma, and choriocarcinoma.
Dygerminomas are the most common type and are particularly prominent in patients diagnosed with Symptoms: Bloating, abdominal distention, ascites, dyspareunia. The book aims to provide an overview of current knowledge regarding germ cell tumors.
It deals with the clinical presentations, treatment modalities, the biology and genetics of germ cell tumors in children and adults.
Most chapters are focused on testicular germ cell tumors whose incidence has been increasing in young males. Included are reviews on the pathogenesis, risk factors, diagnosis Author: Angabin Matin.
Germ cell tumors in the testes of an adolescent male commonly present as an enlarging, solid mass, which may be painful. Within the ovaries, germ cell tumors can usually be distinguished from ovarian cysts, which are much more common, using ultrasound.
Germ cell tumors can spread to lymph nodes, lung, liver, and brain. Advances in the Biosciences, Volume Germ Cell Tumours III documents the proceedings of the Third Germ Cell Tumor Conference held in Leeds, UK on SeptemberThis book focuses on germ cell tumors, which can be cancerous or non-cancerous tumors that normally occur inside the Edition: 1.
Human germ cell tumours (GCTs) are derived from stem cells of the early embryo and the germ line. They occur in the gonads (ovaries and testes) Cited by: 8. Intracranial Germ Cell Tumours:II. Partial Transmission Block Technique patients with localized germinoma achieving com- plete response to primary chemotherapy.
A boost to the primary site then follows using a three-field by: Germ cell tumors are rare. Germ cell tumors account for about 2 to 4 percent of all cancers in children and adolescents younger than age Germ cell tumors can spread (metastasize) to other parts of the body.
The most common sites for metastasis are the lungs. Childhood central nervous system (CNS) germ cell tumors form from germ cells (a type of cell that forms as a fetus develops and later becomes sperm in the testicles or eggs in the ovaries). Learn about the signs, tests to diagnose, and treatment of pediatric germ.
Childhood extracranial germ cell tumors form from germ cells in parts of the body other than the brain. A germ cell is a type of cell that forms as a fetus (unborn baby) develops.
These cells later become sperm in the testicles or eggs in the ovaries. This summary is about germ cell tumors that form in parts of the body that are extracranial (outside the brain).
Matsukado Y, Abe H, Tanaka R, et al. Cisplatin, vinblastine and bleomycin (PVB) combination chemotherapy in the treatment of intracranial malignant germ cell tumors—a preliminary report of a phase II study—The Japanese Intracranial Germ Cell Tumor Study by: 3.
Rogers PC, Olson TA, Cullen JW, et al. Treatment of children and adolescents with stage II testicular and stages I and II ovarian malignant germ cell tumors: A pediatric intergroup study—Pediatric Oncology Group and Children's Cancer Group J Clin Oncol.
; – [Google Scholar]Cited by: This article covers germ cell tumours, often abbreviated GCT, which classically arise in the gonads (ovary, testis). They are also found in the midline and make appearances in neuropathology (e.g. pineal gland) and in the mediastinum.
Germ cell brain tumors are tumors, usually cancerous, that arise in the pineal or suprasellar region of the brain.
Different types of these germ cells cause different types of tumors, including the following: These tumors start and grow mainly in two areas in the center of the brain: However, a germ cell brain tumor can spread to other parts of. Highly specific for germ cell tumors but also seen in ovarian germ cell neoplasms; occasionally in acute leukemia, embryonal rhabdomyosarcoma, neuroepithelioma Chromosome has identical arms, probably from misdivision of centromere Extra copies of 12p associated with tumor progression and treatment failure, particularly in nonseminomatous germ.
The American Joint Committee on Cancer (AJCC) TNM classification and the International Federation of Gynecology and Obstetrics (FIGO) staging system for germ cell tumors are listed below (see Tables 1 and 2). Malignant germ cell tumors of the ovary follow the same staging system as epithelial ovarian and primary peritoneal cancers.
Keywords: germ cell neoplasia in situ, germ cell tumour, postpubertal-type teratoma, spermatocytic tumour Introduction Since the publication of the last World Health Organi-zation (WHO) Classiﬁcation of Tumours of the Urinary System and Male Genital Organs in ,1 there have been a number of advances in our knowledge of theFile Size: 1MB.
Introduction. Testicular cancers are generally grouped into three broad categories with type I testicular germ cell tumours (TGCTs) being observed primarily in neonatal boys and young children and consisting of benign teratomas and malignant yolk sac tumours III TGCT, also called spermatocytic seminomas, affect older men above 50 years of age and are derived from a slow growing Cited by: 9.Management of paediatric extracranial germ-cell tumours carries a unique set of challenges.
Germ-cell tumours are a heterogeneous group of neoplasms that present across a wide age range and vary in site, histology, and clinical behaviour.
Patients with germ-cell tumours are managed by a diverse array of specialists. Thus, staging, risk stratification, and treatment approaches for germ-cell Cited by: 9.Results and conclusions Germ cell tumours were significantly associated with cryptorchidism in males (OR=, 95% CI: –), but not with any other specific CA in either sex.
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